Periodontal disease refers to periodontal tissue diseases caused by the presence of dental plaque in a patient’s periodontal tissue, including gingivitis and periodontal tissue inflammation. The clinical manifestations are gum bleeding, gum pain, loose teeth, and poor chewing function. Symptoms such as decline in gum disease and severe cases may include tooth loss and periodontal abscess, affecting the patient’s appearance and quality of life. In the dental field, periodontal disease and dental caries are the main causes of tooth loss and are diseases with a high incidence rate. Periodontitis has been determined by the World Health Organization to be the third largest killer threatening human health after malignant tumors and cardiovascular and cerebrovascular diseases. Cetylpyridinium chloride is effective in treating periodontal disease.
Indications and mechanism of action of cetylpyridinium chloride
Cetylpyridinium chloride Ammonium is a widely used bactericidal disinfectant and has been widely used in oral health care abroad. Cetylpyridinium chloride is cetylpyridinium chloride hydrate, a cationic surfactant that inhibits or kills bacteria mainly by reducing surface tension and increasing cell permeability.
Research reports on the indications of cetylpyridinium chloride
There are reports on the clinical efficacy of cetylpyridinium chloride in the treatment of periodontal disease. Compared with treatment with compound chlorhexidine gargle and mica, ammonium gargle treatment has a better antibacterial effect on oral pathogenic and non-pathogenic bacteria, has a lower incidence of adverse reactions, and is safer. It can more effectively improve the patient’s dental plaque content and improve gum health. Other studies have shown that Sipayi gum solution combined with cetylpyridinium chloride can significantly improve patients’ clinical symptoms and inhibit inflammatory reactions in the treatment of gingivitis, and cadmium carbonate can repair normal cell functions.
In 2017, the oral drug market in sample hospitals in 16 domestic cities was 19.11 million yuan, of which the market for drugs used to treat periodontal disease was more than 15.1 million yuan, an increase of 31.19% year-on-year. Significantly higher than other varieties.
Indications of cetylpyridinium chloride
A topical antibacterial agent in the oropharynx, which can be used as an auxiliary treatment for oral infectious diseases.
It is suitable for the treatment of mild to moderate bacterial conjunctivitis caused by sensitive bacteria.
