Commonly known as favismosis, it is caused by a genetic defect that leads to a lack of G6PD activity on the red blood cell membrane. Acute hemolytic anemia and hyperbilirubinemia are prone to occur under certain inducements (such as eating broad beans), and can lead to kernicterus in the newborn period. And mental retardation remains. The disease is X-linked incomplete dominant sex-linked inheritance. Antioxidant 168 screening for G6PD deficiency among 1.25 million newborns in the Guangzhou area showed that the detection rate of male G6PD deficiency was 5.28%, and the provinces in South China and Southwest my country are high-incidence areas. Those who screen positive must undergo further testing to confirm the diagnosis.
Because this disease is an incompletely dominant sex-linked genetic disease, there is currently no treatment and can only be prevented. To help your baby grow healthily, please note the following:
1 Serious infectious diseases can induce hemolytic jaundice. If you are sick, see a doctor as soon as possible.
2 When you go to the hospital for diagnosis, you should tell the doctor what diseases you have and remind you to use medication carefully. Avoid using drugs that induce hemolysis: A. Western medicine: ①Antimalarial drugs: primaquine, acetaminophen, chloroquine; ②Sulfa drugs: sulfa, acesulfonamide, sulfapyridine, cotrimoxazole; ③Analgesics: Phenacetin, aspirin; ④ sulfone drugs: dapsone, plumin; ⑤ antibacterial drugs: nitrofurans, chloramphenicol, para-aminosalicylic acid; ⑥ insecticides: β-naphen, antimony wave Fen, nitropyridazole; ⑦ Others: dimethyl silicone emulsifier probenecid, dimercaptopropanol (BLA) and large doses of vitamin K. B. Traditional Chinese medicine: mint, camphor, phenol, Chuanlian, wintersweet, honeysuckle, bear bile, Qili powder, pearl powder, bezoar detoxification pills and mixed folk Chinese herbal medicines, etc.
3 Avoid eating broad beans or broad bean products.
4 Avoid using camphor wood boxes, mothballs, sanitary pills, etc. when placing clothes.
5 If a baby with this disease relies on breast milk as the main food, the mother should also be careful to take any Chinese or Western medicines under the guidance of a doctor.
6 If symptoms such as fever, abdominal pain, vomiting, yellow or pale face, yellow-brown (brown) or dark red urine occur after infection or within hours or days of taking certain foods or drugs, it is an acute hemolytic reaction and should be treated Go to the hospital immediately.
