Aluminum magnesium carbonate is a commonly used antacid in clinical practice. It can quickly neutralize gastric acid, has a mild and long-lasting effect, maintains the pH in the stomach at the optimal calcium carbonate physiological environment, and can combine with bile acids and adsorb pepsin. , inhibit bile acid reflux, and continuously prevent bile acid and pepsin from damaging the stomach. In addition, aluminum magnesium carbonate is also a protective agent for the gastric mucosa, which can stimulate the gastric mucosa to synthesize prostaglandins, enhance the protective effect of the gastric mucosa, and promote the healing of gastric lesions. It is mainly used in the clinical treatment of reflux esophagitis, gastric, and duodenal disease. It can effectively improve symptoms such as nausea, vomiting, acid reflux, heartburn, early satiety, fullness, heartburn and other acid-related diseases such as intestinal ulcer, bile reflux gastritis, functional indigestion, acute and chronic gastritis.
Aluminum Magnesium Carbonate Side Effects Precautions
Aluminum Magnesium Carbonate should be Chew it and swallow it 1-2 hours after a meal, if you have stomach discomfort or before going to bed. You can also chew it and take it with a small amount of water. Only after chewing can the medicine adhere to the surface of the gastric mucosa, isolate gastric acid and protect the gastric mucosa. Taking it 1-2 hours after a meal can avoid the impact of food on the efficacy of the drug. It can also neutralize a large amount of gastric acid secreted after a meal and inhibit bile reflux. Do not drink a lot of water within half an hour after taking the medicine to avoid washing away the protective film of the medicine. Wait until the protective film is stable and completely formed before drinking an appropriate amount of water. In addition, when taking aluminum magnesium carbonate, you should also pay attention to the posture of taking the medicine. It is best to lie still for half an hour after taking the medicine, which can slow down the gastric emptying speed, prolong the local action time of the medicine, and improve the efficacy. In addition, taking aluminum magnesium carbonate with iron preparations, tetracycline, cimetidine, ranitidine, famotidine, deoxycholic acid, digoxin and other drugs at the same time can form a precipitate and affect the efficacy of the drug. It is recommended to take it in advance or Delay 1-2 hours before taking.
Side effects of aluminum magnesium carbonate
Aluminum magnesium carbonate is a macromolecular drug that acts on the surface of the gastrointestinal tract after oral administration and rarely absorbs pyridine bis throughout the body. Hydrochloride is absorbed, so systemic adverse reactions are less, and short-term use is safe and tolerable. Larger doses can cause an increase in the number of stools and the stool becomes soft and mushy. Long-term use can cause constipation and hypermagnesemia. , osteoporosis, vitamin A deficiency, insomnia, headache, mental disorders and other adverse reactions. Therefore, long-term use of aluminum magnesium carbonate should be avoided, and continuous use should not exceed 8 weeks.
In short, aluminum magnesium carbonate is a commonly used antacid and gastric mucosal protector in clinical practice. It is used to relieve common symptoms of acid-related diseases. It is recommended to chew it 1-2 hours after a meal and half a day after taking the medicine. Avoid drinking a lot of water every hour, and lie still for half an hour after taking the medicine to improve the therapeutic effect. Although aluminum magnesium carbonate is almost not absorbed into the blood and rarely causes systemic adverse reactions, long-term use may cause constipation, osteoporosis, vitamin A deficiency, insomnia, mental disorders and other adverse reactions. Therefore, long-term use should be avoided, and continuous use should not exceed 8 weeks.
