Aluminum magnesium carbonate and sodium bicarbonate are commonly used clinical antacids. They are alkaline drugs. After oral administration, they can neutralize excess gastric acid, increase gastric pH, eliminate the irritating damage of gastric acid, and inhibit pepsin. It is active and relieves symptoms such as acid reflux, heartburn, belching, fullness, and stomach pain caused by high gastric acidity. Of course, there are some differences between them.
What is the difference between aluminum magnesium carbonate and sodium bicarbonate? Mechanism of action:
Sodium bicarbonate mainly relieves the symptoms of high gastric acid by neutralizing gastric acid. Its effect is quick and short-lived. Aluminum magnesium carbonate can quickly neutralize gastric acid, but the action lasts for a long time. It can also absorb bile acids and adhere to the gastric mucosa. It forms a protective barrier at the damaged site to prevent pepsin from damaging the stomach, enhances the role of mucosal protective factors, promotes mucosal repair, and exerts a protective effect on the gastric mucosa.
What is the difference between aluminum magnesium carbonate and sodium bicarbonate? Indications:
Sodium bicarbonate can neutralize gastric acid and reduce gastric acidity, but the effect is short-lived and has severe adverse reactions. It can only be used to improve symptoms related to high gastric acid. Aluminum magnesium carbonate can quickly, gently and permanently neutralize gastric acid, and has The protective effect of gastric mucosa can not only improve gastric discomfort symptoms related to gastric acid, but can also be used to treat reflux esophagitis, gastric and duodenal ulcers, acute and chronic gastritis, and bile acid-related diseases. In addition, sodium bicarbonate can alkalize urine, promote the excretion of uric acid and sulfa drugs, prevent the formation of crystalluria and kidney stones, and can be used as an auxiliary treatment for hyperuricemia and gout.
What is the difference between aluminum magnesium carbonate and sodium bicarbonate? Medication time:
Sodium bicarbonate has a short-lived effect, and the best time to take it is when symptoms appear or are about to appear, such as taking it orally between meals or before going to bed. Aluminum magnesium carbonate has a mild and long-lasting effect, and has a protective effect on the gastric mucosa. It should be taken 1-2 days after a meal. Chew it every hour before going to bed and when you have stomach discomfort.
What is the difference between aluminum magnesium carbonate and sodium bicarbonate? Security:
In terms of safety, oral sodium bicarbonate neutralizes gastric acid and produces a large amount of carbon dioxide, which can easily cause adverse reactions such as belching, flatulence, and secondary increased gastric acid secretion. Long-term use of sodium bicarbonate can increase the sodium load in the body, lead to water and sodium retention, tissue edema, and induce or aggravate lithium metaborate hypertension and heart failure. Long-term use of sodium bicarbonate can promote the transfer of potassium ions into cells, leading to hypokalemia. Long-term use of sodium bicarbonate can also increase urine pH and increase the risk of phosphate stones. Therefore, sodium bicarbonate should not be taken for a long time. Aluminum magnesium carbonate in the amount of therapeutic agent di-tert-butyl dicarbonate is almost not absorbed in the gastrointestinal tract and is safe and well tolerated. Taking large doses can lead to increased stool frequency and soft mushy stools, and occasionally dry mouth, constipation, For patients with loss of appetite, regular doses will not affect the concentrations of aluminum and magnesium in the serum. Compared with sodium bicarbonate, aluminum magnesium carbonate is more suitable for the long-term treatment of digestive system diseases.
In short, aluminum magnesium carbonate and sodium bicarbonate are commonly used antacids in clinical practice. They mainly relieve symptoms related to high gastric acid by neutralizing gastric acid. Compared with sodium bicarbonate, aluminum magnesium carbonate also has a protective effect on the gastric mucosa. , suitable for reflux esophagitis, gastric and duodenal ulcers, chronic gastritis and other digestive tract diseases. The therapeutic dose of aluminum magnesium carbonate is almost not absorbed in the gastrointestinal tract, has good safety and tolerance, and has no systemic adverse effects. Reactions are rare and are more suitable for long-term treatment. In addition, sodium bicarbonate can alkalize urine and promote uric acid excretion, and can be used as an auxiliary treatment for hyperuricemia and gout.
