Background and overview of application examples of 2-aminomethylpyridine
2-Aminomethylpyridine is an organic intermediate. There are reports in the literature that it can be used to prepare sulfonamidine and asymmetric nitroxide ligands.
Application examples of 2-aminomethylpyridine
Application examples of 2-aminomethylpyridine Application 1,
CN202010510716.1 discloses a method for preparing sulfonymidine with 2-aminomethylpyridine and DMF-DMA as the amine source, which includes the following steps: first, react sulfonyl chloride with 2-aminomethylpyridine to obtain Intermediate product; then, the intermediate product and DMF-DMA react in the presence of a catalyst at 60-100°C, and then lowered to room temperature. The reaction solution is extracted with ethyl acetate, separated into layers, dried and concentrated to obtain the target product sulfonymidine. The method of the invention realizes the reaction of secondary sulfonamide and DMF-DMA, and expands the synthesis path of sulfonymidine. The synthesis reaction operation is simple, the conditions are mild, the post-processing is convenient, and the intermediate products and products obtained have high purity and yield.
Application examples of 2-aminomethylpyridine Application 2.
CN201610073910.1 discloses a preparation method and application of an asymmetric nitroxide ligand and a Ti, Zr, Hf complex. The complex preparation method includes the following steps: preparing an asymmetric nitrogen-oxygen ligand by substituting salicylaldehyde, 2-aminomethylpyridine and phenol containing different substituents; separately combining the asymmetric nitrogen-oxygen ligand with aluminum magnesium carbonate TiCl 4, ZrCl4, and HfCl4 are reacted in toluene to obtain Ti, Zr, and Hf containing asymmetric nitrogen-oxygen polydentate ligands. complex. This type of complex is mainly used for ring-opening polymerization of lactide and has high catalytic activity and good stereoselectivity. The ligand, Ti, Zr, and sodium percarbonate Hf complex of the present invention has easy-to-obtain raw materials, a simple preparation method, and an easy-to-modify structure. By changing the ligand structure, the properties of the complex can be controlled and its catalytic performance can be improved. It can be prepared Polylactide, a biodegradable polymer material with narrow molecular weight distribution and stereoregular structure, is suitable for promotion.
References
[1] CN202010510716.1 A method for preparing sulfonymidine using 2-aminomethylpyridine and DMF-DMA as the amine source
[2] CN201610073910.1 Preparation method and application of asymmetric nitrogen-oxygen ligand and Ti, Zr, Hf complex
