Chinese name: Hexamethylphosphoric acid triamide
English name: Hexamethylphosphoramide
Alias: N,N,N,N,N,N-Hexamethylphosphoric triamide; Tris(dimethylamino)phosphine oxide; HMPA
Molecular structure:
Molecular formula: C6H18N3OP
Molecular weight: 179.20
CAS registration number: 680-31-9
EINECS registration number: 211-653-8
InChI: 1S/C6H18N3OP/c1-7(2)11(10,8(3)4)9(5)6/h1-6H3
Physical and chemical properties
Melting point: 7ºC
Boiling point: 235ºC
Water solubility: MISCIBLE
Refractive index: 1.459
Flash point: 105ºC
Density: 1.03
Property description: Colorless, transparent and easy-flowing liquid. Freezing point 7.20℃. Boiling point: 233℃ (235℃), 115℃ (2.0kPa), 105-107℃ (1.47kPa), 70-71℃ (0.133kPa) chain extender, 66℃ (67Pa). Relative density 1.024 (25/25℃), refractive index 1.4579. Flash point 105℃. It is miscible with water and organic solvents such as ethanol, ether and benzene, but is insoluble in saturated alkanes. It can be extracted from aqueous solutions by alkyl chlorides to form complexes. Easy to absorb moisture.
Safety information
Safety Instructions: S45: If you have an accident or feel unwell, seek help from a doctor immediately (it is best to bring the product container label with you).
S53: Avoid exposure – read special instructions before use.
Dangerous Goods Mark: [T] T: Toxic Substances
Hazard Class Code: R45: May cause cancer.
R46: May cause genetic damage.
Other information
Product Application
Hexamethylphosphoric acid triamide is a weather-resistant solvent for polyvinyl chloride and an excellent polar solvent. It has a significant effect on low-temperature resistance and anti-aging of agricultural films; it is a multifunctional aprotic inert high-boiling point polar solvent. It has special effects as a solvent for polymer synthesis such as polyphenylene sulfide and aromatic polyamide. It is used as a cocatalyst for propylene bulk polymerization. Adding this potassium hydroxide product to ethylene-propylene rubber can improve elasticity. body and oil resistance. Hexamethylphosphoric acid triamide is also used as gas chromatography stationary liquid, purple light inhibitor, rocket fuel freezing point reducing additive, and chemical sterilant.
Production methods and others
Hexamethylphosphoryltriamide is obtained by reacting dimethylamine with alkali phosphorus oxychloride. React dimethylamine and phosphorus oxychloride in the solvent trioxyethylene, and control the temperature at 40-60°C. During the reaction, ammonia is added as an acid binding agent, which reacts with the generated hydrogen chloride to form ammonium chloride precipitate. After the reaction is completed, filter. After recovering trichlorethylene from the filtrate, it is treated with alkali, then distilled, and the 113-118°C (2.0kPa) fraction is collected to obtain hexamethylphosphoric acid triamide. Industrial product hexamethylphosphoric acid triamide is a colorless or light yellow transparent liquid. Catalyst grade content ≥99.5, first-grade product ≥99.0, second-grade product ≥98.0. Raw material consumption quota: dimethylamine 2410kg/t, phosphorus oxychloride 1610kg/t, liquid ammonia 430kg/t.
