Background and overview[1]
Glycerol iron phosphate is a yellow or yellow-green crystalline powder. This product is insoluble in water or ethanol. This product contains glycerol iron phosphate, calculated as iron (Fe), it should be 13.0% to 18.0%. It is widely used in health products and nutritional supplements.
Identification[1]
(1) Take 1g of this product, add 100ml of water, heat to dissolve, let cool, take 10ml, add 10ml of dilute nitric acid and 5ml of ammonium molybdate test solution, boil, and leave to form a yellow precipitate.
(2) Take 1g of this product, add 10ml of hydrochloric acid to dissolve it, add water to dilute to 100ml, take 10ml, add 1 drop of potassium ferrocyanide test solution, it will appear dark blue.
Content determination[1]
Take about 0.5g of this product, weigh it accurately, place it in a stoppered conical flask, add 15ml of water to dissolve, add 1ml of sulfuric acid, let cool to 15℃, add potassium permanganate test solution dropwise until the solution turns pink. And continue for 15 seconds, add 2g of potassium iodide, 5ml of hydrochloric acid, seal tightly, let stand in the dark for 5 minutes, add 60ml of water, titrate with sodium thiosulfate titrant (0.1mol/L) to near the end point, add 2ml of starch indicator solution, Continue the titration until the blue color disappears, and correct the titration results with a blank test. Each 1ml of sodium thiosulfate titrant (0.1mol/L) is equivalent to 5.585mg of Fe.
Apply[2-4]
CN201410749997.0 discloses a health product for enhancing the immunity of infants and young children, including: 100~180g of purified water, 12~22g of lysine hydrochloride, 15~30g of vitamin B12, 34~66g of goat milk, and 8~ of zinc sulfate. 16g, rice kernel 22~46g, folic acid 2~6g, orchid 22~26g, sucrose 14~16g, sweet-scented osmanthus 14~25g, glycerol iron phosphate 10~26g, almond 8~16g, lotus root node 10~15g. Through the above method, the health care product of the present invention that enhances the immunity of infants and young children has a wide variety of ingredients and has good safety performance. It can effectively supplement the nutrients needed by infants and young children, increase their own ability to resist viral infections, and reduce their exposure to external infections. times, effectively improving the immunity and resistance of infants and young children.
CN201410024837.X discloses a preparation method of oral liquid. The preparation method is as follows: obtain simple syrup; take vitamin B2, mix it with the second water, add alkali to dissolve, and obtain the first premix; take L-lysine hydrochloride, nicotinic acid, zinc sulfate, glycerol iron phosphate, and citron Acid, vitamin B1, vitamin B6, preservatives, folic acid and third water are mixed to obtain a second premix; vitamin E is mixed with ethanol to obtain a vitamin E solution; simple syrup, first premix, and second premix are obtained. Mix the mixture with the vitamin E solution, heat it for a second time, cool it, then add food essence and the remaining amount of water, mix well, filter, and adjust the pH value to 3.1~3.9 to get it. The method provided by the invention increases the solubility of vitamin B2 in the medicinal liquid by adding alkali to dissolve vitamin B2, making it possible to increase the vitamin B2 content in the oral liquid. The oral liquid has stable properties and can be stored for a long time without precipitation.
CN20 cosmetic grade silicone oil emulsion 1210528359.7 discloses a preparation method of milk food for patients with acute pancreatitis, raw material formula, casein 15~17.5 tripotassium citrate 0.93~1.35 trisodium citrate 1~1.44 trisodium citrate Magnesium 0.35~0.41 Baking soda 0.92~1.08 Sucrose 4~6 Industrial additives Children’s grade oat flour 8~12 Glycerol iron phosphate 0.38~0.42 Skim milk powder 53.80~65.42, added water-soluble vitamins (mg/100g), vitamin B61.9 ~2.1, anti-skin disease vitamins 14~16, vitamin C 65~75, mixed into powder form. When patients eat this product, they must dissolve it in water (12g/100ml) at 70~80℃, heat it until it boils, and then cool it to 35~37℃ before eating. There are special considerations for patients with acute pancreatitis. The efficacy helps absorption, digestion, low cost and cost saving.
Main reference materials
[1] Glycerol Iron Phosphate – Chemical Drugs Landmark Upgraded to National Standard 6 Volumes
[2] CN201410749997.0 Health products to enhance the immunity of infants and young children
[3] CN201410024837.X Preparation method of oral liquid
[4] CN201210528359.7 Preparation method of milk food for patients with acute pancreatitis
