Water-soluble Fosfomycin Calcium_Industrial Additive

The chemical name of Fosfomycin Calcium is: (—)-(1R, 2S)-1,2-epoxypropylphosphate calcium salt monohydrate. A broad spectrum antibiotic. It is the antibiotic with the smallest molecular weight so far. It has a unique structure and has no cross-resistance with any antibiotics. It is known as a green antibiotic. It is a bactericide during the breeding period. When combined with cefotaxime sodium, it has a significant synergistic effect, especially against E. coli. Powerful antibacterial activity.
This product is a soluble powder of fosfomycin calcium, prepared by spray drying method. The physical and chemical properties of the product are PVC resin powder latest price stable. After drying, the product has good dispersion, fluidity and solubility.
【Technical indicators】
Properties Appearance: This product is white crystalline powder; odorless, soluble in water
Water score: no more than 12%
Glycols: Glycols should not exceed 2.0%
Containing quantity: calculated as dry product, the potency of every 1 mg of fosfomycin calcium water-soluble powder shall not be less than 288 fosfomycin units
【Pharmacology and Toxicology】
This product is a broad-spectrum antibiotic that inhibits the early synthesis of bacterial cell walls, causing bacterial cell wall synthesis to be inhibited and leading to their death. It has a certain antibacterial effect on most Gram-positive bacteria and pigmented carbon black Gram-negative bacteria, especially showing excellent antibacterial activity against drug-resistant Escherichia coli, aerobacteria, Proteus, Salmonella, and Staphylococcus aureus. This product kills bacteria quickly and has no cross-resistance with any antibiotics.
【Pharmacology】
​ 30% to 40% of fosfomycin calcium is absorbed from the gastrointestinal tract after oral administration, and its absorption is not affected by food. It is widely distributed in tissue fluids, with the highest concentration in the kidneys, followed by the heart, lungs, liver, etc. It can also enter the chest, abdominal cavity, and bronchial secretions.
【Notes】
Combination with β-lactams, aminoglycosides and other antibiotics often has a synergistic effect and can reduce or delay the development of bacterial resistance.
[Storage Storage] APIs should be protected from light, dry and sealed, and stored in a cool and dark place
[Withdrawal period] Pigs: 5 days, chickens: 7 days
【Validity period】Three years