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preparation of sitagliptin impurity 13_industrial additives

background and overview[1] sitagliptin, chemical name (2r)-4-oxo-4-[3-trifluoromethyl-5,6-dihydro[1,2,4]triazole[4 , 3-a]pyrazin-7(8h)-yl]-1-(2,4,5-tr…

preparation of 2-fluoro-4-iodoaniline_industrial additives

background and overview[1] 2-fluoro-4-iodoaniline is one of the most important intermediates in the dye industry. in the dye industry, it can be used …

preparation of 3-bromo-1,3,4,5-tetrahydro-2h-1-benzazepine-2-one_industrial additives

background and overview[1] 3-bromo-1,3,4,5-tetrahydro-2h-1-benzazepine-2-one is an intermediate in the synthesis of benazepril hydrochloride. benazepr…

preparation of benzenesulfonyl chloride_industrial additives

background and overview[1] benzenesulfonyl chloride is a white flake crystal with a melting point of 69-71°c. it is an important organic synthesis dru…

preparation of m-methoxypropiophenone_industrial additives

background and overview[1] me-methoxypropiophenone is a key intermediate used in the production of the drug tapentadol. tapentadol is a novel oral ana…

application of (r)-2-(aminoethyl)-4-chlorophenol_industrial additives

background and overview[1][2] (r)-2-(aminoethyl)-4-chlorophenol is a chiral organic intermediate, which can be prepared by reductive amination of 2-hy…

preparation of α-methylbenzonitrile_industrial additives

background and overview[1] α-methylbenzonitrile, also called 2-phenylpropionitrile, can be used to synthesize 2-phenylpropionic acid, which is widely …

preparation and application of 6,7-dihydro-4(5h)-benzofuranone_industrial additives

background and overview[1] 6,7-dihydro-4(5h)-benzofuranone is an important pharmaceutical intermediate. it can be prepared by the reaction of 1,3-cycl…

preparation of 2-(2-methoxy-4-niphenyl)-3-(4-niphenyl)-5-(2,4-disulfobenzene)-2h-tetrazole monosodium salt_industry additive

background and overview[1] 2-(2-methoxy-4-niphenyl)-3-(4-niphenyl)-5-(2,4-disulfobenzene)-2h-tetrazole monosodium salt, wst-8, referred to as wst-8, i…

(2s-cis)-(+)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepine-4(5h)-one preparation_industrial additives

background and overview[1] (2s-cis)-(+)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepine-4(5h) -ketone is a key intermediate in the synth…

preparation and application of [1,1′-bis(diphenylphosphine)ferrocene]palladium dichloride dichloromethane complex_industrial additives

background and overview[1] [1,1′-bis(diphenylphosphine)ferrocene]palladium dichloride dichloromethane complex (pd(dppf)cl2·ch2 cl2) is a bimetallic so…

preparation methods and applications of m-chloroperoxybenzoic acid_industrial additives

background and overview[1-2] metachloroperoxybenzoic acid is a commonly used oxidizing agent in organic synthesis. it can oxidize alkenes, carbonyl co…

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